Subventricular Zone Involvement Characterized by Diffusion Tensor Imaging in Glioblastoma.

Bart RJ Van Dijken, Jiun-Lin Yan, Natalie R Boonzaier, Chao Li, Peter Jan Van Laar, Anouk Van Der Hoorn & Stephen Price
Background Glioblastomas have a poor prognosis, possibly due to a subpopulation of therapy resistant stem cells within the heterogeneous glioblastoma. As the subventricular zone is the main source of neural stem cells, we aimed at characterising the subventricular zone using DTI to demonstrate subventricular zone involvement in glioblastoma. Methods We prospectively included 93 patients with primary glioblastomas who underwent preoperative DTI. The non-enhancing high FLAIR signal was used to describe the infiltrative tumour margin. We...
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