Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis

E Paige, Jessica Barrett, Lisa Pennells, Michael Sweeting, P Willeit, Emanuele Di Angelantonio, V Gudnason, BG Nordestgaard, BM Psaty, U Goldbourt, LG Best, G Assmann, JT Salonen, PJ Nietert, WM Verschuren, EJ Brunner, RA Kronmal, V Salomaa, SJ Bakker, GR Dagenais, S Sato, J-H Jansson, J Willeit, A Onat, AG De La Cámara … & Angela Wood
The added value of incorporating information from repeated measurements of blood pressure and cholesterol for cardiovascular disease (CVD) risk prediction has not been rigorously assessed. We used data from the Emerging Risk Factors Collaboration on 191,445 adults (38 cohorts from across 17 countries with data from 1962-2014) with > 1 million measurements of systolic blood pressure, total cholesterol and high-density lipoprotein cholesterol; over a median 12 years of follow-up, 21,170 CVD events occurred. Risk prediction...
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