A Novel Method for Rapid and Quantitative Mechanical Assessment of Soft Tissue for Diagnostic Purposes: A Computational Study

J Palacio-Torralba, DW Good, Grant Stewart, SA McNeill, RL Reuben & Y Chen
Biological tissues often experience drastic changes in their microstructure due to their pathophysiological conditions. Such microstructural changes could result in variations in mechanical properties, which can be used in diagnosing or monitoring a wide range of diseases, most notably cancer. This paves the avenue for non-invasive diagnosis by instrumented palpation although challenges remain in quantitatively assessing the amount of diseased tissue by means of mechanical characterization. This paper presents a framework for tissue diagnosis using...

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