Longitudinal associations between marine omega-3 supplement users and Coronary Heart Disease in a UK population-based cohort

Maria Lentjes, RH Keogh, AA Welch, Angela Mulligan, Robert Luben, Nicholas Wareham & Kay-Tee Khaw
Objectives: Assess the association between marine omega-3 polyunsaturated fatty acid (n 3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. Design: Prospective cohort study, with three exposure measurements over 22 y. Setting: Norfolk-based European Prospective Investigation into Cancer (EPIC-Norfolk, UK). Participants: 22,035 men and women from the general population, 39-79 y at recruitment. Exposure: Supplement use was assessed in three questionnaires (1993-1998; 2002-2004; 2004-2011). Participants were grouped into non-supplement...
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