Placebo response in trichotillomania

JE Grant, Samuel Chamberlain, SA Redden, BL Odlaug, M Van Ameringen, DD Dougherty, NJ Keuthen & SW Kim
Background: Trichotillomania is a functionally impairing, often overlooked disorder with no FDA-approved medications indicated for its treatment. The ability of clinical trials to detect beneficial effects of pharmacologic treatment in trichotillomania has been hampered by the high placebo response rate. Very little is known about baseline demographic and clinical characteristics that may be predictive of placebo response in such patients. Methods: 104 participants assigned to placebo were pooled from five double-blind trials conducted at three...

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