The effect of communicating the genetic risk of cardiometabolic disorders on motivation and actual engagement in preventative lifestyle modification and clinical outcome: a systematic review and meta-analysis of randomised controlled trials

Sherly X Li, Zheng Ye, Kevin Whelan & Helen Truby
Genetic risk prediction of chronic conditions including obesity, diabetes and cardiovascular disease currently has limited predictive power but its potential to engage healthy behaviour change has been of immense research interest. We aimed to understand if the latter is indeed true by conducting a systematic review and meta-analysis investigating whether genetic risk communication affects motivation and actual behaviour change towards preventative lifestyle modification. We included all RCTs since 2003 investigating the impact of genetic risk...
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