Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Are Not Specific Biomarkers for Mild CT-Negative Traumatic Brain Injury

Jussi P Posti, Iftakher Hossain, Riikka SK Takala, Hilkka Liedes, Virginia Newcombe, Joanne Outtrim, Ari J Katila, Janek Frantzen, Henna Ala-Seppala, Jonathan Coles, Anna Kyllonen, Henna-Riikka Maanpaa, Jussi Tallus, Peter Hutchinson, Mark Van Gils, David Menon, Olli Tenovuo & TBIcare Investigators
Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) have been studied as potential biomarkers of mild traumatic brain injury (mTBI). We report the levels of GFAP and UCH-L1 in patients with acute orthopedic injuries without central nervous system involvement, and relate them to the type of extracranial injury, head magnetic resonance imaging (MRI) findings, and levels of GFAP and UCH-L1 in patients with CT-negative mTBI. Serum UCH-L1 and GFAP were longitudinally measured from...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.