A semi-automatic method for the extraction of the portal venous input function in quantitative dynamic contrast-enhanced CT of the liver

Andrew Gill, NJ Hilliard, ST Hilliard, Martin Graves, David Lomas & Ashley Shaw
OBJECTIVES To aid the extraction of the portal venous input function (PVIF) from axial dynamic contrast-enhanced CT images of the liver, eliminating the need for full manual outlining of the vessel across time-points. METHODS A cohort of 20 patients undergoing perfusion CT imaging of the liver were examined. Dynamic images of the liver were reformatted into contiguous thin slices. A region of interest (ROI) was defined within a transverse section of the portal vein on...

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