Reannotation of CCA-ends, initiator tRNAs, and other CAU-anticodon tRNAs of prokaryotic genomes in tRNAdb-CE 0.8

David H. Ardell & Ya-Ming Hou
Background: While the CCA sequence at the mature 3′ end of tRNAs is conserved and critical for translational function, a genetic template for this sequence is not always contained in tRNA genes. In eukaryotes and archaea, the CCA ends of tRNAs are synthesized post-transcriptionally by CCA-adding enzymes. In bacteria, tRNA genes template CCA sporadically. Results: In order to understand the variation in how prokaryotic tRNA genes template CCA, we re-annotated tRNA genes in tRNAdb-CE database...
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