Reward anticipation in individuals with subclinical psychotic experiences: A functional MRI approach.

Stijn Michielse, Iris Lange, Jindra Bakker, Liesbet Goossens, Simone Verhagen, Silvia Papalini, Marieke Wichers, Ritsaert Lieverse, Koen Schruers, Therese Van Amelsvoort, Jim Van Os, Graham K Murray & Machteld Marcelis
Previous research in patients with psychotic disorder has shown widespread abnormalities in brain activation during reward anticipation. Research at the level of subclinical psychotic experiences in individuals unexposed to antipsychotic medication is limited with inconclusive results. Therefore, brain activation during reward anticipation was examined in a larger sample of individuals with subclinical psychotic experiences (PE). Participants in the PE-group were included based on CAPE scores. A sample of emerging adults aged 16-26 years (n =...
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