Application of Single Cell Technologies to the Study of Hematopoiesis

Bertie Gottgens
The Gottgens group uses a combination of experimental and computational approaches to study how transcription factor networks control the function of blood stem cells and how mutations that perturb such networks cause diseases. The group's current research focuses on (i) single cell genomics of early blood development, (ii) computer models of the transcriptional landscape of blood stem cell differentiation, (iii) transcriptional consequences of leukaemogenic mutations, and (iv) molecular characterization of human blood stem cell populations...
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