Molecular mechanisms of gene regulation in response to environmental and developmental stimuli

Sandra Schick
Biological processes such as cellular differentiation or response to environmental stimuli require gene expression adaptations. Such plastic remodeling is achieved by the application of diverse mechanisms that involve transcriptional and epigenetic modulations. In order to gain deeper insights into the molecular changes, the expression and chromatin alterations occurring in response to UV irradiation, circadian rhythm and neuronal cell fate commitment were investigated in this thesis. To this end, molecular experiments and high-throughput sequencing techniques were...
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