Phobalysin: fisheye view of membrane perforation, repair, chemotaxis and adhesion

Gisela Von Hoven, Amable J. Rivas & Matthias Husmann
Phobalysin P (PhlyP, for photobacterial lysin encoded on a plasmid) is a recently described small %26beta;-pore forming toxin of Photobacterium damselae subsp. damselae (Pdd). This organism, belonging to the family of Vibrionaceae, is an emerging pathogen of fish and various marine animals, which occasionally causes life-threatening soft tissue infections and septicemia in humans. By using genetically modified Pdd strains, PhlyP was found to be an important virulence factor. More recently, in vitro studies with purified...
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