Polymeric nanocapsules as versatile platform for the development of new dendritic cell-directed nanovaccines

David Paßlick
Therapeutic vaccination against tumor diseases remains a major challenge in immune therapy. The effective activation of dendritic cells by a combination of distinctly acting adjuvants and antigens is essential for success. While conventional vaccine formulations lack the efficiency to trigger sufficient T cell responses in a therapeutic tumor treatment, nanovaccines may offer unique properties to tackle that challenge. In this doctoral thesis, we report the use of polymeric nanocapsules as a versatile platform for the...
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