Functionally modified (Deoxy)Ribonucleotides : synthesis and study of physicochemical and biological properties

Isabell Hellmuth
Understanding and controlling the role of RNA in processes of human health and disease, apart from basic cellular mechanisms, is of immense value. Many severe cases are still in need for optimized therapy strategies, a gap, which could be filled in the near future by promising therapeutic RNA applications. Especially the design of tailored siRNA and mRNA strategies towards personal therapy presents an encouraging point of vantage. The development of such techniques requires fundamental knowledge...
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