Case control study on childhood leukemia in Lower Saxony, Germany - basic considerations, methodology, and summary of results

Peter Kaatsch, Uwe Kaletsch, Frank Krummenauer, Rolf Meinert, Anke Miesner, Hans Günter Haaf & Jörg Michaelis
In two municipalities in Lower Saxony statistically valid clusters were observed, which attracted great public interest. Committees were set up to initiate a large variety of on-the-spot-investigations. Finally, it was decided to conduct a case control study throughout Lower Saxony to explore potential risk factors which might explain the observed clusters. A limited number of already established and currently discussed hypotheses was chosen for investigation. The study was based on patients registrated at the German...
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