Does This Patient Have a Family History of Cancer? An Evidence-Based Analysis of the Accuracy of Family Cancer History

Harvey J Murff, David R Spigel & Sapna Syngal
Context: A family history of certain cancers is associated with an increased risk of developing cancer. Both cancer screening and genetic services referral decisions are often based on self-reported pedigree information. Objective: To determine the accuracy of self-reported family cancer history information. Data Sources English-language articles were retrieved by searching MEDLINE (1966-June 2004) using Medical Subject Headings family, genetic predisposition to disease, medical history taking, neoplasm, and reproducibility of results. Additional articles were identified through...
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