Associations between vascular risk factors, carotid atherosclerosis and cortical volume and thickness in older adults

Valerie Cardenas, Bruce Reed, Linda Chao, Helena Chui, Nerses Sanossian, Charles DeCarli, Wendy Mack, Joel Kramer, Howard Hodis, Mingzhu Yan, Michael Buonocore, Owen Carmichael, William J. Jagust & Michael W. Weiner
Data from healthy and cognitively impaired elderly, enriched for cerebrovascular disease. Background and Purpose: To investigate whether the Framingham Cardiovascular Risk Profile (FCRP) and carotid artery intima-media thickness (CIMT) are associated with cortical volume and thickness. Results: 152 subjects (82 men) were aged 78 (±7) years old, 94 had a CDR of 0, 58 had a clinical dementia rating (CDR) of 0.5 and the mean mini-mental status examination (MMSE) was 28 ±2. FCRP score was...
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