Justin Cotney. Epigenomic Atlas of Early Human Craniofacial Development

Justin Cotney & Andrea Wilderman
Defects in patterning during human embryonic development frequently result in craniofacial abnor- malities. The gene regulatory programs that build the craniofacial complex are likely controlled by in- formation located between genes and within intronic sequences. However, systematic identification of regulatory sequences important for forming the hu- man face has not been performed. Here, we describe comprehensive epigenomic annotations from human embryonic craniofacial tissues and systematic comparisons with multiple tissues and cell types. We identified thousands...
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