Ophir Klein/Derk Joester. Enamel atlas: systems-level amelogenesis tools at multiple levels

Ophir Klein/Derk Joester Ophir Klein/Derk Joester
Enamel defects, whether congenital, acquired, or environmental in origin, are associated with a significant cost to society and also have profound psychological impacts. Despite significant progress over the last decade, the developmental process that gives rise to enamel, known as amelogenesis, remains poorly understood. We have identified at least two factors that have delayed progress, and which we propose to address in this application. One is that existing mouse reagents, which provide the primary model...
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