Activity of human neural crest enhancer near FOXI2 in E11.5 transgenic mouse embryo – Tg(hg38_chr10:127774583-127775373::LacZ).Joanna Wysocka, Licia Selleri & Tomasz Swigut
Tg(hg38 _chr10:127774583-127775373::LacZ) with human biased activity in the 2nd branchial arch and an expansion of expression in the frontonasal process when compared to the activity of the equivalent chimp enhancer. LacZ signal was also consistently observed in the periocular mesenchyme, distal maxillary and mandibular 1st branchial arch, anterior forelimb and hindlimb buds, and dorsal root ganglia.
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