Activity of chimp neural crest enhancer near COL13A1 in E11.5 transgenic mouse embryo – Tg(panTro4_chr10: 68198369-68199194::LacZ).

Joanna Wysocka, Licia Selleri & Tomasz Swigut
Tg(panTro4_chr10: 68198369- 68199194::LacZ) chimp neural crest enhancer with activity in the forebrain, midbrain, hindbrain, trigeminal (V) ganglion, and midgut. This enhancer lacks the expression in the frontonasal process, optic cup, branchial arches, heart field, limb buds, and somites that is observed with the equivalent human enhancer, demonstrating a human species-specific bias when comparing these two species.
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