Activity of human neural crest enhancer near BMPER in E11.5 transgenic mouse embryo - Tg(hg38_chr7:33486073-33487607::LacZ)

Joanna Wysocka, Licia Selleri & Tomasz Swigut
Tg(hg38_chr7:33486073-33487607::LacZ) human neural crest enhancer primarily exhibiting expression in the trigeminal ganglion and nerve. 2/8 embryos also express LacZ in the medial frontonasal prominence, periocular mesenchyme, branchial arches, forelimb buds, and somites. This enhancer has relatively low expression in the human frontonasal prominence, demonstrating a species-specific bias in P. troglodytes when these two species are compared.
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